Dermatologic negative effects have actually consisted of psoriasiform rashes, pemphigus-like lesions, angioedema of the face and also mucous membranes, pityriasis-like eruptions, alopecia, exfoliative dermatitis, photosensitivity, bullous or lichenoid eruptions, as well as erythematous eruptions. Rarely, worsened Kaposi's sarcoma sores, oncolysis, pemphigus vulgaris, and also Henoch-Schonlein Purpura have actually been stated. A situation of poisonous skin necrolysis has also been stated. [Ref]Captopril Capoten. Capoten.
Worried system side impacts have included dysgeusia (0.3 % to 4.0 %) and also migraine (approximately 4 %). Situations of Guillain-Barre neuropathy and also parkinsonism have actually been stated. [Ref]
A 57-year-old male with hypertension as well as modest liquor usage established a sensorimotor loss related to an analytical spine liquid pleocytosis 3 months after starting captopril treatment. A complete work-up was otherwise plain. The patient at some point called for mechanical air flow, at which time captopril was discontinued. The syndrome solved completely over the following six weeks. Nerve transmission rate as well as electromyography findings followed a demyelinating neuropathy of the Guillain-Barre kind. A 75-year-old male with hypertension as well as cardiac arrest developed an evasion gait, relaxing tremors, mask face, and cogwheel rigidness many days after starting captopril therapy. A full work-up was unremarkable. The parkinsonian signs and symptoms resolved after captopril was stopped. [Ref]